San Francisco (3-0) rides a three-game winning streak into a matchup with Arizona (1-2) on Sunday, October 1, 2023 at Levi's Stadium. The 49ers are undoubtedly the favorites in this one, with the spread posted at 14.5 points. The over/under in the outing is set at 44 points.

There will be plenty of live betting opportunities this week when the 49ers go up against the Cardinals. Before making any in-game bets, you'll want to check out the stats and trends that we list below.

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Cardinals vs. 49ers Quarter-By-Quarter Betting Tips

1st Quarter

  • The Cardinals have been winning two times and have trailed one time at the end of the first quarter this season.
  • In three games this year, the 49ers have had the lead after the first quarter two times and been tied one time.
  • San Francisco's offense is averaging 6.7 points in the first quarter this year. On the other side of the ball, it is surrendering two points on average in the first quarter.

2nd Quarter

  • The Cardinals have lost the second quarter one time and outscored their opponent two times in three games this season.
  • The 49ers have outscored their opponent in the second quarter in two games this season, and they've been outscored in the second quarter in one game.
  • San Francisco's offense is averaging 11.3 points in the second quarter this year. Defensively, it is surrendering eight points on average in the second quarter.

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3rd Quarter

  • The Cardinals have lost the third quarter two times and won one time in three games this year.
  • In three games this year, the 49ers have lost the third quarter one time and outscored their opponent two times.
  • Offensively, San Francisco is averaging 4.3 points in the third quarter (16th-ranked) this year. It is giving up two points on average in the third quarter (sixth-ranked) on defense.

4th Quarter

  • The Cardinals have won the fourth quarter in one game this season. Meanwhile, they've been outscored in the fourth quarter in two games.
  • In three games this season, the 49ers have outscored their opponent in the fourth quarter in every single game.
  • San Francisco's offense is averaging 7.7 points in the fourth quarter this year. On defense, it is surrendering two points on average in that quarter.

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Cardinals vs. 49ers Half-By-Half Scoring Trends

1st Half

  • This season, the Cardinals have led after the first half in two games (1-1 in those contests) and have been behind after the first half in one game (0-1).
  • At the conclusion of the first half, the 49ers have been winning two times and been knotted up one time.

2nd Half

  • Digging into second-half scoring this season, the Cardinals have outscored their opponent in the second half in one game and have been outscored in the second half in two games.
  • In three games this year, the 49ers have scored more than their opponent in the second half in every game. They sport a 3-0 record in those contests.
  • San Francisco's offense is averaging 12 points in the second half this year. Defensively, it is allowing four points on average in the second half.

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