Arizona Cardinals remain perfect, defeat San Francisco 49ers 17-10 in Glendale

Arizona Cardinals running back James Conner (6) scores a touchdown against the San Francisco...
Arizona Cardinals running back James Conner (6) scores a touchdown against the San Francisco 49ers during the first half of an NFL football game, Sunday, Oct. 10, 2021, in Glendale, Ariz. (AP Photo/Darryl Webb)(Darryl Webb)
Updated: Oct. 10, 2021 at 3:50 PM MST
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GLENDALE, AZ (3TV/CBS 5/AP) -- Kyler Murray and the Cardinals continue rolling, with another win against the rookie Trey Lance and the 49ers on Sunday afternoon.

The game was mirrored primarily by defense, with both offenses struggling at times during the game. Murray threw for 239 yards and one touchdown, his lowest passing game this season so far. Lance passed for 192 yards and one interception, and rushed for 89 yards.

Budda Baker came up with a interception on the Niners first drive of the game when Lance attempted to go deep for Travis Benjamin, but was met with six Cardinals defenders downfield. Shortly after, a James Conner touchdown put the Cardinals ahead 7-0 in the first quarter. Huge stops by the Cardinals defense kept the Niners scoreless, including a stop on fourth and goal by Isaiah Simmons and Tanner Vallejo when Lance attempted to rush in for the touchdown.

Rondale Moore may have a potential catch of the year, after showing off his toe-tapping skills with a difficult ball thrown by Murray. The catch sparked insanity on social media, with many left scratching their head on how Moore kept the ball in bounds.

A missed field goal by Matt Prater kept the score at 10-0 right before halftime. Cardinals and Niners traded punts to open up the third quarter, then a touchdown by the Niners late in the third quarter opened up the game once again. Former Sun Devil Brandon Aiyuk caught a 26-yard pass from Lance, and the Niners stomped down the field for a Deebo Samuel touchdown to put the game at 10-7.

However, Cardinals defense kept the Niners at bay, coming up with four 4th down stops and one interception. A fourth quarter touchdown from DeAndre Hopkins gave the Cardinals life once again, putting them up 17-7. Another stop by the Cardinals on third down forced the Niners to kick a field goal late in the fourth quarter, with the Cardinals up 17-10.

Niners rookie quarterback Trey Lance had an up-and-down first start, making some impressive plays with his arm and feet. But the San Francisco offense struggled in many of the biggest moments, converting 1 of 5 chances on fourth down. Lance was making his first career start in place of the injured Jimmy Garoppolo, inactive for the game because of a calf injury suffered in last week’s loss to Seattle.

The Cardinals will travel to Cleveland to take on Baker Mayfield and the Browns next Sunday at 1:05 p.m.