The heat warnings will be in effect from 10 a.m. to 8 p.m. both Thursday and Friday and include the Phoenix area, Yuma, Florence, Casa Grande, Wickenburg and Quartzsite.
The National Weather Service is forecasting record or near-record temperatures.
Phoenix is expected to reach 109 degrees on Thursday and 112 degrees on Friday. Parker should hit a whopping 114 degrees on Friday.
The hot temperatures will make heat stroke more likely for those doing anything strenuous outdoors and can be dangerous for the elderly who don't have air conditioning.
According to the Arizona Department of Health, about 1,400 people are affected by heat-related illness each year, their conditions so severe that they wind up in the emergency room. On average, between 30 and 80 people die of heat-related illness every summer.
People are urged to limit outdoor activity and dress for the heat.